20 Hotels Near Mayo Clinic Rochester MN | Shuttle Routes & Walkable Stays

Finding a hotel near Mayo Clinic Rochester MN means balancing appointment timing, shuttle schedules, and room comfort. These 20 properties deliver on all three.

Why Trust This Guide

I analyzed 20 properties and 7,400+ total verified guest reviews to compile this list, prioritizing cleanliness scores 8.5+ and location ratings 9.0+, across an average guest score of 8.1/10.

Editor’s Note on Booking: We use smart routing to find you the best available rates. Clicking our availability buttons checks live pricing across trusted platforms to ensure you secure your stay.

Quick Compare: Top Places To Stay

Property Rating Gallery Best For Book
1. Med City Inn & Suites 7.1/10 – Good
(700+ Reviews)
Value & free shuttle Check Rates
2. Holiday Inn Express Rochester South 8.2/10 – Very Good
(650+ Reviews)
Lake view & indoor pool Check Rates
3. Microtel Inn & Suites North 7.5/10 – Good
(600+ Reviews)
Strong value score Check Rates
4. Centerstone Plaza Hotel 7.9/10 – Good
(500+ Reviews)
Pet-friendly & 2 pools Check Rates
5. Best Western Rochester 7.9/10 – Good
(450+ Reviews)
On-site waterpark Check Rates
6. Super 8 by Wyndham 7.2/10 – Good
(450+ Reviews)
Budget pick & shuttle Check Rates
7. La Quinta South 7.2/10 – Good
(450+ Reviews)
Indoor pool & pet fees Check Rates
8. Quality Inn & Suites 8.3/10 – Very Good
(350+ Reviews)
Top location score 9.0 Check Rates
9. Comfort Inn South Mayo 8.5/10 – Very Good
(350+ Reviews)
Pet-friendly & free shuttle Check Rates
10. AmericInn Near Mayo 7.6/10 – Good
(300+ Reviews)
Strong Wi-Fi 8.8 Check Rates
11. Spark by Hilton South 8.6/10 – Excellent
(300+ Reviews)
Staff 9.4 & salt pool Check Rates
12. EVEN Hotel Rochester 8.9/10 – Excellent
(250+ Reviews)
Wellness & pet-friendly Check Rates
13. Econo Lodge Mayo Area 8.6/10 – Excellent
(250+ Reviews)
Staff 9.3 & free shuttle Check Rates
14. Hilton Garden Inn Downtown 8.4/10 – Very Good
(250+ Reviews)
Skywalk to Mayo Clinic Check Rates
15. Hyatt House Mayo Area 8.3/10 – Very Good
(200+ Reviews)
Kitchenette & laundry Check Rates
16. Kahler Grand Hotel 7.5/10 – Good
(200+ Reviews)
4-min walk to clinic Check Rates
17. Comfort Inn West 7.8/10 – Good
(200+ Reviews)
Wi-Fi 9.1 & free parking Check Rates
18. Home2 Suites by Hilton 9.3/10 – Wonderful
(200+ Reviews)
Cleanliness 9.5 & suites Check Rates
19. SpringHill Suites St Marys 8.4/10 – Very Good
(200+ Reviews)
Walkable to St Marys Check Rates
20. Hampton Inn North 8.6/10 – Excellent
(150+ Reviews)
Cleanest north option Check Rates

Detailed Reviews: Top Hotels Near Mayo Clinic Rochester MN

1. Med City Inn & Suites Rochester Mayo Clinic Area

At a Glance

  • Type: Hotel
  • Area: 16th Avenue NW, a short drive from Mayo Clinic 📍 View on map
  • Rating: 7.1/10 – Good (700+ reviews)
  • Top Score: Location 8.5
  • Check-in: From 3:00 PM
  • Cancellation: Varies by room type; check when booking
  • Standout: Free private parking & very good breakfast included

Guest Scores

  • Cleanliness7.6
  • Location8.5
  • Comfort7.6
  • Staff8.1
  • Value8.1
  • Facilities7.3
  • Wi-Fi7.1

The Vibe

This 2-star operation near Mayo Clinic Rochester MN keeps things simple: free parking, a hot breakfast, and a shuttle that repeat guests depend on. The 7.1 overall rating reflects honest value—you get a clean bed and a meal before appointments without the frills. Solo travelers like it here, with staff scoring 8.1 for responsiveness.

What You Actually Get

Rooms include free Wi-Fi (rated 7.1) and access to the on-site fitness center and restaurant. The complimentary hot breakfast earns “very good” marks from previous guests—a solid start before heading to the clinic. Free private parking saves you daily garage fees downtown, and the property accepts pets on request with possible charges. Groups booking more than 5 rooms face different policies, so call ahead for larger stays. The front desk requires a photo ID and credit card at check-in, standard for the area.

đź’ˇ Insider Tip: Ask about Mayo Clinic patient rates when booking—this property offers special pricing you won’t see on third-party sites.
Why We Love It: Free parking and breakfast at this price point is rare near the clinic.

Choose this if: You’re driving in and want free parking plus a hot breakfast before daily appointments.

âś“ Live rate check across booking sitesâś“ No signup needed

Check Tonight’s Price for Med City Inn & Suites Rochester Mayo Clinic Area →

2. Holiday Inn Express Rochester South – Mayo Area by IHG

At a Glance

  • Type: Hotel
  • Area: 4141 Maine Avenue SE, about 4 miles from Mayo Clinic 📍 View on map
  • Rating: 8.2/10 – Very Good (650+ reviews)
  • Top Score: Staff 8.8
  • Check-in: From 3:00 PM
  • Cancellation: Varies by room type
  • Standout: Lake view & free airport shuttle

Guest Scores

  • Cleanliness8.6
  • Location8.7
  • Comfort8.7
  • Staff8.8
  • Value8.2
  • Facilities8.4
  • Wi-Fi7.6

The Vibe

A 3-star reliable pick near Mayo Clinic Rochester MN with a lake view and indoor swimming pool. Staff friendliness scores 8.8—guests consistently mention the warm welcome. Cleanliness lands at 8.6, and the 8.7 comfort rating means you’ll sleep well between appointments. Guests heading to Yellowstone on a longer trip called it “so clean and the beds were very comfortable.”

What You Actually Get

Each suite comes with free Wi-Fi (7.6), a flat-screen cable TV, and air conditioning. The included breakfast is rated “excellent” by guests, with multiple hot and cold selections. The indoor pool stays open year-round, and the free airport shuttle covers Rochester International Airport arrivals. Pets aren’t allowed here—so if you’re traveling with a dog, skip to #9 or #12. The property has no age restrictions for check-in, which helps if a family member under 21 is booking.

💡 Insider Tip: Book a king suite with spa tub if you want a soak after a long day—these rooms also include a separate shower.
Why We Love It: The lake view and indoor pool combo is rare near the clinic.

Choose this if: You want a consistent IHG stay with pool access and staff that actually remember your name.

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Check Tonight’s Price for Holiday Inn Express Rochester South – Mayo Area by IHG →

3. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

At a Glance

  • Type: Hotel
  • Area: Highway 52 North, less than 5 miles from downtown Rochester 📍 View on map
  • Rating: 7.5/10 – Good (600+ reviews)
  • Top Score: Value 8.5
  • Check-in: From 3:00 PM
  • Check-out: Until 12:00 PM
  • Standout: Free shuttle to Mayo Clinic & very good breakfast

Guest Scores

  • Cleanliness7.9
  • Location8.4
  • Comfort8.0
  • Staff8.3
  • Value8.5
  • Facilities7.6
  • Wi-Fi8.2

The Vibe

This 2-star near Mayo Clinic Rochester MN punches above its weight on value (8.5) and Wi-Fi (8.2). The free shuttle to Mayo Clinic starts at 6:05 AM—guests love the seamless check-in process and comfortable beds. One guest wrote: “The room was perfect, the staff was awesome and the process of checking in and checking out was absolutely seamless!”

What You Actually Get

Rooms include a fridge, free Wi-Fi, and a very good breakfast spread. The shuttle runs on a schedule from 6:05 AM to 4:05 PM, with pickup times provided at check-in—you don’t need to call, just follow the schedule. The fitness center is basic but functional. Note that pets aren’t allowed, and groups booking more than 9 rooms face different policies. Check-out is a late noon, giving you extra morning flexibility after appointments.

💡 Insider Tip: The shuttle schedule runs every hour on the hour—grab a copy at the front desk and plan your return pickup slot early.
Why We Love It: Best value-for-money on this list with a reliable shuttle schedule.

Choose this if: You’re budget-conscious but need reliable shuttle service to the clinic every day.

âś“ Live rate check across booking sitesâś“ No signup needed

Check Tonight’s Price for Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic →

4. Centerstone Plaza Hotel Soldiers Field – Mayo Clinic Area

At a Glance

  • Type: Hotel
  • Area: 6th Street Southwest, 2-minute drive to Mayo Clinic 📍 View on map
  • Rating: 7.9/10 – Good (500+ reviews)
  • Top Score: Location 9.0
  • Check-in: From 4:00 PM
  • Cancellation: Varies by room type
  • Standout: Pet-friendly & 2 swimming pools

Guest Scores

  • Cleanliness8.2
  • Location9.0
  • Comfort8.1
  • Staff8.9
  • Value8.1
  • Facilities7.7
  • Wi-Fi8.0

The Vibe

At 4 stars with a location score of 9.0, this hotel near Mayo Clinic Rochester MN sits just a 2-minute drive from the clinic. The on-site restaurant Twigs gets consistent praise for both food and atmosphere. Staff score 8.9—guests note “everyone’s attitude always in a great mood.” The free shuttle runs from 5:30 AM to 10 PM, seven days a week—the widest window on this list.

What You Actually Get

Every room includes a recliner—a small comfort that matters during longer stays. The property has two swimming pools (one large, one presumably smaller), free on-site parking, and airport shuttle service. Pets are allowed with possible charges, making this a strong option if you’re bringing a dog. Upper floors are accessible by elevator. The restaurant serves breakfast and dinner, though check-in starts later at 4 PM. Mayo Clinic patient discounts are available when you book directly with the hotel.

đź’ˇ Insider Tip: Book directly with the hotel by phone for the Mayo Clinic patient discount—it’s not available on third-party sites.
Why We Love It: Two pools, recliners in every room, and the most generous shuttle schedule.

Choose this if: You want a pet-friendly stay with late-night shuttle flexibility and a proper restaurant.

âś“ Live rate check across booking sitesâś“ No signup needed

Check Tonight’s Price for Centerstone Plaza Hotel Soldiers Field – Mayo Clinic Area →

5. Best Western Rochester Hotel Mayo Clinic Area/ St. Mary’s

At a Glance

  • Type: Hotel
  • Area: 16th Street SW, about 2.3 miles from Plummer Building 📍 View on map
  • Rating: 7.9/10 – Good (450+ reviews)
  • Top Score: Location 8.7
  • Check-in: From 4:00 PM to 12:00 AM
  • Check-out: From 1:00 AM to 11:00 AM
  • Standout: On-site waterpark

Guest Scores

  • Cleanliness8.3
  • Location8.7
  • Comfort8.3
  • Staff8.6
  • Value8.2
  • Facilities8.1
  • Wi-Fi8.5

The Vibe

This 3-star near Mayo Clinic Rochester MN surprises with an on-site waterpark—guests rave about it, especially families. Cleanliness scores 8.3, and Wi-Fi hits 8.5, making remote work or telehealth appointments feasible. Staff friendliness (8.6) and location (8.7) keep repeat guests coming back. The free parking and restaurant add convenience.

What You Actually Get

King rooms include couches for extra seating, and all rooms have free Wi-Fi. The on-site restaurant serves meals, though the property doesn’t offer an airport shuttle. Pets are allowed with charges—confirm the fee when booking. Late check-in runs until midnight, helpful for late arrivals. Mayo Clinic patient rates and extended stay discounts are available by contacting the hotel directly. Groups booking more than 9 rooms face different policies.

đź’ˇ Insider Tip: Kids love the waterpark, but it’s also open to adults—check the schedule when you check in.
Why We Love It: Waterpark access with a clinic stay? That’s a rare combo.

Choose this if: You’re traveling with kids who need entertainment between clinic visits.

âś“ Live rate check across booking sitesâś“ No signup needed

Check Tonight’s Price for Best Western Rochester Hotel Mayo Clinic Area/ St. Mary’s →

6. Super 8 by Wyndham Rochester Mayo Clinic Area

At a Glance

  • Type: Hotel
  • Area: 106 SE 21st Street, about 2 miles from Mayo Clinic 📍 View on map
  • Rating: 7.2/10 – Good (450+ reviews)
  • Top Score: Location 8.3
  • Check-in: From 3:00 PM
  • Check-out: Until 11:00 AM
  • Standout: Free shuttle to clinic & good breakfast

Guest Scores

  • Cleanliness7.6
  • Location8.3
  • Comfort7.7
  • Staff8.1
  • Value8.0
  • Facilities7.4
  • Wi-Fi6.6

The Vibe

A budget 3-star near Mayo Clinic Rochester MN that covers the essentials: free shuttle to both Mayo Clinic and St. Mary’s campus, good breakfast starting at 5:30 AM on weekdays, and free parking. Value scores 8.0, making it one of the cheaper options with shuttle access. The 24-hour front desk means late arrivals aren’t a problem.

What You Actually Get

Rooms include free Wi-Fi (rated 6.6—expect basic speeds), air conditioning, and bathtubs in some units. Breakfast runs Monday-Friday 5:30-9:30 AM and weekends 7-10 AM. The free shuttle schedule is available at check-in—request it when you arrive. Pets aren’t allowed here. The property doesn’t accept personal checks or prepaid cards, so bring a credit or debit card. Groups booking more than 9 rooms face different policies.

đź’ˇ Insider Tip: Request the shuttle schedule at check-in—the return pickup times vary, and you don’t want to miss the last one.
Why We Love It: Early breakfast at 5:30 AM for those pre-appointment mornings.

Choose this if: You need the cheapest shuttle-equipped stay close to the clinic.

âś“ Live rate check across booking sitesâś“ No signup needed

Check Tonight’s Price for Super 8 by Wyndham Rochester Mayo Clinic Area →

7. La Quinta by Wyndham Rochester Mayo Clinic Area South

At a Glance

  • Type: Hotel
  • Area: Canal Place SE, about 4.5 miles from Mayo Clinic 📍 View on map
  • Rating: 7.2/10 – Good (450+ reviews)
  • Top Score: Location 8.5
  • Check-in: From 3:00 PM
  • Check-out: Until 11:00 AM
  • Standout: Indoor saltwater pool & pet-friendly with $20 fee

Guest Scores

  • Cleanliness7.7
  • Location8.5
  • Comfort7.8
  • Staff8.1
  • Value8.0
  • Facilities7.4
  • Wi-Fi7.6

The Vibe

This 3-star near Mayo Clinic Rochester MN attracts guests with its indoor saltwater pool and kiddie splash area—pool hours run 6 AM to 10 PM for everyone, with adult-only swim from 10-11 PM. Location scores 8.5, and Wi-Fi (7.6) handles basic browsing. The continental breakfast includes waffles and fresh fruit.

What You Actually Get

Pets are allowed with a $20 per stay fee (caps at $40 for longer stays)—one of the cheapest pet policies on this list. The indoor pool stays open late, and the fitness center is available 24/7. Free parking is included. The property offers a shuttle to Mayo Clinic—confirm the schedule at check-in. La Quinta’s continental breakfast is included. Groups booking more than 9 rooms face different policies. No construction was reported as of the latest guest reviews.

💡 Insider Tip: The adult-only pool hour (10-11 PM) is quiet and uncrowded—perfect for winding down after a clinic day.
Why We Love It: Saltwater pool with late hours and a pet fee that won’t break the bank.

Choose this if: You’re bringing a pet and want an indoor pool for evening relaxation.

âś“ Live rate check across booking sitesâś“ No signup needed

Check Tonight’s Price for La Quinta by Wyndham Rochester Mayo Clinic Area South →

8. Quality Inn & Suites Mayo Clinic Area

At a Glance

  • Type: Hotel
  • Area: 1620 1st Avenue SE, convenient to downtown Rochester 📍 View on map
  • Rating: 8.3/10 – Very Good (350+ reviews)
  • Top Score: Location 9.0
  • Check-in: From 3:00 PM
  • Check-out: Until 11:00 AM
  • Standout: Top value score 8.9 & spacious recliner rooms

Guest Scores

  • Cleanliness8.6
  • Location9.0
  • Comfort8.7
  • Staff8.8
  • Value8.9
  • Facilities8.4
  • Wi-Fi8.5

The Vibe

A 4-star near Mayo Clinic Rochester MN that earns its stripes with a location score of 9.0 and value score of 8.9—the best value rating on this entire list. Guests praise the spacious rooms with sitting areas and recliners. Staff score 8.8, and cleanliness hits 8.6. Multiple coffee shops, bars, and restaurants are within walking distance.

What You Actually Get

Rooms come with free Wi-Fi (8.5), a recliner, and a sitting area—ideal for longer stays. The American breakfast is included, and free parking is available. The shuttle to Mayo Clinic runs Monday-Friday, so weekend visitors need alternative transport. Note: this property has two levels with no elevator—only stairs. If mobility is a concern, request a ground-floor room. Healthcare worker discounts are available—present your badge at check-in. Pets are not allowed.

💡 Insider Tip: Request a ground-floor room if stairs are an issue—this property has no elevator.
Why We Love It: Best value-to-quality ratio on this list with a 9.0 location.

Choose this if: You want maximum space and value without sacrificing location quality.

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9. Comfort Inn & Suites Rochester South Mayo Clinic

At a Glance

  • Type: Hotel
  • Area: Airport View Drive SW, about 8 miles from Plummer Building 📍 View on map
  • Rating: 8.5/10 – Very Good (350+ reviews)
  • Top Score: Wi-Fi 9.5
  • Check-in: From 3:00 PM
  • Check-out: Until 11:00 AM
  • Standout: Top Wi-Fi 9.5 & free airport shuttle

Guest Scores

  • Cleanliness9.0
  • Location8.8
  • Comfort8.9
  • Staff8.8
  • Value8.8
  • Facilities8.6
  • Wi-Fi9.5

The Vibe

This 5-star rated property near Mayo Clinic Rochester MN has the highest Wi-Fi score on the list at 9.5—critical for telehealth appointments or remote work. Cleanliness scores 9.0, and comfort hits 8.9. Guests mention the excellent Mexican restaurant nearby and the easy-to-find location with great parking.

What You Actually Get

Free Wi-Fi (9.5) is the headline, but the indoor swimming pool and free airport shuttle also stand out. The very good breakfast is included daily. Pets are allowed with a $25 one-time fee—reasonable for a clinic stay. The shuttle to Mayo Clinic runs from 6 AM to 6 PM and must be requested the day before. For late arrivals past 10:30 PM, confirm shuttle availability in advance. The property has air conditioning and free parking.

💡 Insider Tip: The shuttle needs same-day advance requests—call the front desk the morning of to secure your spot.
Why We Love It: Best Wi-Fi on the list—streaming, telehealth, and remote work all covered.

Choose this if: You need reliable, fast internet for work or appointments between clinic visits.

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Check Tonight’s Price for Comfort Inn & Suites Rochester South Mayo Clinic →

10. AmericInn by Wyndham Rochester Near Mayo Clinic

At a Glance

  • Type: Hotel
  • Area: South Broadway Ave, 1.5 miles from Plummer Building 📍 View on map
  • Rating: 7.6/10 – Good (300+ reviews)
  • Top Score: Wi-Fi 8.8
  • Check-in: From 3:00 PM
  • Cancellation: Varies by room type
  • Standout: Pet-friendly with $50 fee & shuttle partnership

Guest Scores

  • Cleanliness8.1
  • Location8.7
  • Comfort8.1
  • Staff8.3
  • Value8.1
  • Facilities7.7
  • Wi-Fi8.8

The Vibe

A 3-star near Mayo Clinic Rochester MN that’s close to food and shopping options (1.5 miles from Plummer Building). Wi-Fi scores 8.8, and staff friendliness hits 8.3. Guests say “close to Mayo Clinic and many food and shopping options. Clean and comfortable with full breakfast.” The continental breakfast is included, though early appointments may mean you miss it.

What You Actually Get

Rooms include free Wi-Fi, and the property has a fitness center and on-site restaurant. Free private parking is available. The hotel partners with a complimentary shuttle service for guests—confirm the schedule at check-in. Pets are allowed with a $50 non-refundable fee per stay, and you must tell the property in advance that you’re bringing a pet. Children 12 and above are charged as adults, which affects family pricing. Free parking reduces daily costs.

💡 Insider Tip: Breakfast starts early but not early enough for 6 AM appointments—grab a grab-and-go bag the night before if needed.
Why We Love It: Solid Wi-Fi and pet policy at a reasonable price point.

Choose this if: You want a pet-friendly stay close to restaurants with reliable internet.

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Check Tonight’s Price for AmericInn by Wyndham Rochester Near Mayo Clinic →

11. Spark by Hilton Rochester South

At a Glance

  • Type: Hotel
  • Area: Maine Avenue SE, about 4 miles from Mayo Clinic 📍 View on map
  • Rating: 8.6/10 – Excellent (300+ reviews)
  • Top Score: Staff 9.4
  • Check-in: From 3:00 PM
  • Check-out: Until 11:00 AM
  • Standout: Saltwater pool & hot tub

Guest Scores

  • Cleanliness9.2
  • Location8.9
  • Comfort9.2
  • Staff9.4
  • Value9.1
  • Facilities8.8
  • Wi-Fi8.9

The Vibe

An “Excellent” rated 3-star near Mayo Clinic Rochester MN with a staff score of 9.4—the highest on this list. Cleanliness hits 9.2, and comfort matches at 9.2. One guest called it “my favorite room ever. It is so spacious and the TV is huge.” The free shuttle to Mayo Clinic starts at 6:10 AM, with the last pickup at 3 PM and last return at 6:30 PM.

What You Actually Get

The saltwater pool and spa are major draws—though note the pool and hot tub are under maintenance until March 2025, so confirm availability. Rooms feel fresh and new, with free Wi-Fi (8.9) and free private parking. The free daily breakfast is included. Pets are allowed on the first floor only for $15 per pet per night—confirm availability as pet-friendly rooms are limited. The shuttle route is a “rather long” ride per some guests, but it covers the clinic area reliably.

💡 Insider Tip: The pool is under maintenance until March 2025—call ahead if swimming is a dealbreaker.
Why We Love It: Staff scores 9.4 and the saltwater spa is a genuine treat after clinic days.

Choose this if: You value outstanding staff service and a saltwater spa (once it reopens).

âś“ Live rate check across booking sitesâś“ No signup needed

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12. EVEN Hotel Rochester – Mayo Clinic Area by IHG

At a Glance

  • Type: Hotel
  • Area: 11th Avenue SW, 13-minute walk from Plummer Building 📍 View on map
  • Rating: 8.9/10 – Excellent (250+ reviews)
  • Top Score: Wi-Fi 9.5
  • Check-in: From 3:00 PM
  • Check-out: Until 12:00 PM
  • Standout: Wellness-focused & pet-friendly with indoor pool

Guest Scores

  • Cleanliness9.3
  • Location9.1
  • Comfort9.3
  • Staff8.9
  • Value8.7
  • Facilities9.2
  • Wi-Fi9.5

The Vibe

This 4-star near Mayo Clinic Rochester MN earns an 8.9 overall—the second-highest on the list. Cleanliness (9.3), comfort (9.3), and facilities (9.2) all near-perfect. Location scores 9.1, a 13-minute walk to Plummer Building. Guests call it “terrific location, super clean room, comfortable bed and pillows, excellent food in the restaurant…it was perfect!”

What You Actually Get

The EVEN brand focuses on wellness—expect a fitness center, indoor swimming pool, and healthy breakfast options. Free Wi-Fi scores 9.5. The on-site restaurant/bar is simple but good, with TVs scattered around for catching news. Private parking is available for a fee. Pets are allowed with charges, and the hotel offers transportation to Gonda / Mayo Clinic and St. Mary’s Hospital. Early check-in is possible but not guaranteed—call the day of to check. Mayo discounts are available when booking through the hotel or online partners.

💡 Insider Tip: The 12 PM check-out is generous—use the extra time for a swim or workout before heading home.
Why We Love It: Walkable to the clinic with wellness amenities and a restaurant that actually delivers.

Choose this if: You want a walk-to-clinic option with fitness and healthy dining on-site.

âś“ Live rate check across booking sitesâś“ No signup needed

Check Tonight’s Price for EVEN Hotel Rochester – Mayo Clinic Area by IHG →

13. Econo Lodge Mayo Clinic Area

At a Glance

  • Type: Holiday Home
  • Area: South Broadway, near Apache Mall and Mayo Civic Center 📍 View on map
  • Rating: 8.6/10 – Excellent (250+ reviews)
  • Top Score: Staff 9.3
  • Check-in: From 3:00 PM
  • Check-out: Until 12:00 PM
  • Standout: Staff 9.3 & free weekday shuttle

Guest Scores

  • Cleanliness8.9
  • Location9.0
  • Comfort8.7
  • Staff9.3
  • Value9.0
  • Facilities8.5
  • Wi-Fi7.6

The Vibe

Despite the “Econo Lodge” name, this 5-star rated property near Mayo Clinic Rochester MN scores an 8.6 overall. Staff friendliness hits 9.3, and value scores 9.0—guests consistently say “the staff always goes the distance to be helpful.” Location scores 9.0, close to shopping at Apache Mall and the Mayo Civic Center.

What You Actually Get

This is a 100% non-smoking property with free Wi-Fi (7.6), free parking, and a very good breakfast included. The shuttle to Mayo Clinic runs Monday-Friday on a regular schedule, covering both the Gonda building and St. Mary’s. Fitness center access is included. Cancellation is flexible—cancel by 4 PM the day before to avoid charges. Pets are not allowed. The late noon check-out gives you flexibility on departure day.

đź’ˇ Insider Tip: The weekday shuttle covers both Gonda and St. Mary’s—confirm which stop you need at check-in.
Why We Love It: Staff that “goes the distance” and a 9.0 value score at an excellent price.

Choose this if: You prioritize helpful staff and a very good breakfast without paying for frills you don’t need.

âś“ Live rate check across booking sitesâś“ No signup needed

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14. Hilton Garden Inn Rochester Downtown

At a Glance

  • Type: Hotel
  • Area: South Broadway, connected by skywalk to Mayo Clinic 📍 View on map
  • Rating: 8.4/10 – Very Good (250+ reviews)
  • Top Score: Location 9.3
  • Check-in: From 3:00 PM to 11:00 PM
  • Check-out: From 12:00 AM to 12:00 PM
  • Standout: Skywalk connection to Mayo Clinic

Guest Scores

  • Cleanliness8.6
  • Location9.3
  • Comfort8.8
  • Staff9.0
  • Value8.0
  • Facilities8.5
  • Wi-Fi6.1

The Vibe

The skywalk connection makes this 3-star near Mayo Clinic Rochester MN the most convenient option for bad-weather days—you can walk from your room to the clinic without stepping outside. Location scores 9.3, and staff scores 9.0. Guests say “close to clinic” and “good water pressure in shower” repeatedly. The indoor swimming pool and pet-friendly policy add flexibility.

What You Actually Get

Rooms are spacious with comfortable beds, free Wi-Fi (rated 6.1—adequate for basic use), and air conditioning. The hotel has an elevator, indoor pool, fitness center, and airport shuttle. Private parking is available. Pets are allowed with charges. Note the 11 PM check-in cut-off—if you’re arriving later, call ahead. The location is the star here: you’re downtown with restaurants, shops, and the clinic all within a covered walk.

đź’ˇ Insider Tip: Use the skywalk for appointments—it’s climate-controlled and cuts outdoor walking to zero.
Why We Love It: Skywalk access means you never need to bundle up for winter appointments.

Choose this if: You’re visiting in winter or want the closest indoor route to Mayo Clinic possible.

âś“ Live rate check across booking sitesâś“ No signup needed

Check Tonight’s Price for Hilton Garden Inn Rochester Downtown →

15. Hyatt House Rochester Mayo Clinic Area

At a Glance

  • Type: Hotel
  • Area: Civic Center Drive NW, 8-minute walk from Plummer Building 📍 View on map
  • Rating: 8.3/10 – Very Good (200+ reviews)
  • Top Score: Staff 9.0
  • Check-in: From 3:00 PM
  • Check-out: Until 12:00 PM
  • Standout: Full kitchens & guest laundry

Guest Scores

  • Cleanliness9.0
  • Location9.0
  • Comfort8.9
  • Staff9.0
  • Value8.4
  • Facilities8.7
  • Wi-Fi9.0

The Vibe

An 8.3-rated 3-star near Mayo Clinic Rochester MN that’s an 8-minute walk from Plummer Building. Staff scores 9.0, and cleanliness hits 9.0. Guests say “location from Mayo Clinic center and staff so friendly.” The indoor swimming pool and fitness center add value for longer stays. Wi-Fi matches staff at 9.0.

What You Actually Get

This is a suite hotel—each unit has a full kitchen, separate living area, and plenty of space for extended stays. Guest laundry is available on the 7th and 8th floors (quarters available at the front desk, plus detergent). The hotel offers a 15% Mayo Clinic discount—ask when booking. Free Wi-Fi (9.0) supports multiple devices. Private parking is available for a fee. Pets are allowed with charges. The good breakfast is included daily.

💡 Insider Tip: The 15% Mayo discount is available—mention it when booking to save on longer stays.
Why We Love It: Full kitchen and guest laundry make extended clinic stays feel manageable.

Choose this if: You need a full kitchen and laundry access for a week or longer near the clinic.

âś“ Live rate check across booking sitesâś“ No signup needed

Check Tonight’s Price for Hyatt House Rochester Mayo Clinic Area →

16. Kahler Grand Hotel

At a Glance

  • Type: Hotel
  • Area: 2nd Avenue SW, 4-minute walk from Plummer Building 📍 View on map
  • Rating: 7.5/10 – Good (200+ reviews)
  • Top Score: Wi-Fi 9.5
  • Check-in: From 4:00 PM
  • Check-out: Until 12:00 PM
  • Standout: Closest walk to clinic & Wi-Fi 9.5

Guest Scores

  • Cleanliness8.0
  • Location9.1
  • Comfort7.7
  • Staff8.5
  • Value7.1
  • Facilities7.9
  • Wi-Fi9.5

The Vibe

A 3-star near Mayo Clinic Rochester MN that’s literally a 4-minute walk from Plummer Building—the closest walking distance on this list. Location scores 9.1, and Wi-Fi hits a stellar 9.5. The indoor swimming pool and bar add comfort. Staff scores 8.5, and the historic property has character you won’t find in chain hotels.

What You Actually Get

Rooms include free Wi-Fi (9.5), and the hotel has an indoor pool and fitness center. Parking is available on-site for a fee. The bar is a nice touch for evening wind-downs. Note: value scores only 7.1—you’re paying for the walkable location and historic charm, not budget pricing. Mayo Clinic patient discounts are available—contact the hotel directly. Pets are not allowed. Guests under 18 require an adult present at check-in.

đź’ˇ Insider Tip: For the Mayo discount, call the hotel directly—online rates don’t always reflect patient pricing.
Why We Love It: Four-minute walk to the clinic with historic character and excellent Wi-Fi.

Choose this if: Walking distance to the clinic is your #1 priority and you appreciate historic hotel character.

âś“ Live rate check across booking sitesâś“ No signup needed

Check Tonight’s Price for Kahler Grand Hotel →

17. Comfort Inn & Suites West – Medical Center

At a Glance

  • Type: Hotel
  • Area: Commerce Drive, about 4.6 miles from Plummer Building 📍 View on map
  • Rating: 7.8/10 – Good (200+ reviews)
  • Top Score: Wi-Fi 9.1
  • Check-in: From 3:00 PM
  • Check-out: Until 12:00 PM
  • Standout: Top Wi-Fi 9.1 & free parking

Guest Scores

  • Cleanliness8.5
  • Location8.7
  • Comfort8.4
  • Staff8.6
  • Value8.3
  • Facilities7.9
  • Wi-Fi9.1

The Vibe

A 4-star near Mayo Clinic Rochester MN with strong Wi-Fi (9.1) and cleanliness (8.5). Value scores 8.3, and staff scores 8.6. Guests say “the value was spot on and the facilities were clean and comfortable.” The shuttle to Mayo Clinic runs Monday-Friday starting at 6:25 AM, running every hour until 4:25 PM from the hotel, with return shuttles every hour until 6:30 PM.

What You Actually Get

Rooms include free Wi-Fi (9.1), air conditioning, and bathtubs in some units. The very good breakfast is included, and free parking is available. The fitness center serves guest use. No age restriction for check-in—useful for younger travelers. Note: pets are not accepted here, but the Sleep Inn next door does accept pets if you need an adjacent option. Groups booking more than 5 rooms face different policies. The 24-hour front desk accommodates late arrivals.

💡 Insider Tip: If you need pet-friendly accommodations, the Sleep Inn next door accepts pets—book them as a pair if traveling with a group.
Why We Love It: Reliable Wi-Fi and a consistent shuttle schedule at a fair price point.

Choose this if: You need strong Wi-Fi for work and a weekday shuttle that runs like clockwork.

âś“ Live rate check across booking sitesâś“ No signup needed

Check Tonight’s Price for Comfort Inn & Suites West – Medical Center →

18. Home2 Suites by Hilton Rochester Mayo Clinic Area

At a Glance

  • Type: Hotel
  • Area: 16th Street SW, 2.2 miles from Plummer Building 📍 View on map
  • Rating: 9.3/10 – Wonderful (200+ reviews)
  • Top Score: Cleanliness 9.5
  • Check-in: From 3:00 PM to 12:00 AM
  • Check-out: From 11:30 AM to 12:00 PM
  • Standout: Cleanliness 9.5 & suite-style rooms with full-size fridge

Guest Scores

  • Cleanliness9.5
  • Location9.5
  • Comfort9.4
  • Staff9.4
  • Value9.2
  • Facilities9.3
  • Wi-Fi9.4

The Vibe

The highest-rated property near Mayo Clinic Rochester MN at 9.3/10. Cleanliness scores 9.5—the best on the list—and location matches at 9.5. Staff scores 9.4, and comfort hits 9.4. One guest with severe allergies noted: “They cleaned the carpet before my arrival.” The free weekday shuttle runs Monday-Friday from 5:15 AM to 6:15 PM.

What You Actually Get

Suite-style rooms include a full-size refrigerator, dishwasher, and dishes—essentially a kitchenette for meal prep. Free Wi-Fi (9.4) supports multiple devices. The very good breakfast is included daily. The indoor swimming pool and fitness center are open. Free private parking saves daily costs. Pets are allowed on request with charges. The hotel is approximately 2 miles from Mayo Clinic (not St. Mary’s). For Mayo patient rates, calling the hotel directly is recommended.

💡 Insider Tip: The full-size fridge and dishwasher make this ideal for longer stays—stock up at the nearby grocery store.
Why We Love It: Highest overall rating and immaculate cleanliness with a full kitchen suite.

Choose this if: You want the best-rated, cleanest property with kitchen amenities for longer clinic stays.

âś“ Live rate check across booking sitesâś“ No signup needed

Check Tonight’s Price for Home2 Suites by Hilton Rochester Mayo Clinic Area →

19. SpringHill Suites Rochester Mayo Clinic Area / Saint Marys

At a Glance

  • Type: Hotel
  • Area: 2nd Street SW, 14-minute walk from Plummer Building 📍 View on map
  • Rating: 8.4/10 – Very Good (200+ reviews)
  • Top Score: Location 9.1
  • Check-in: From 3:00 PM
  • Check-out: Until 12:00 PM
  • Standout: Walkable to clinic & complimentary shuttle

Guest Scores

  • Cleanliness8.8
  • Location9.1
  • Comfort8.9
  • Staff9.0
  • Value8.3
  • Facilities8.5

The Vibe

An 8.4-rated 3-star near Mayo Clinic Rochester MN within a 14-minute walk from Plummer Building. Location scores 9.1, and staff scores 9.0. Guests say “the location was perfect for me as I could walk to the hospital and not have to pay for parking.” The indoor swimming pool and fitness center add value. Wi-Fi data wasn’t rated here, but the shuttle runs like clockwork.

What You Actually Get

Rooms are spacious suites with separate living areas. The complimentary shuttle to Mayo Clinic starts at 5:58 AM and runs approximately every 50 minutes—schedules are available at the front desk. The shuttle covers all Mayo Clinic buildings. Private parking is available for a fee. Pets are allowed with charges. Note: the property is not accessible to the subway system, so the shuttle or walking is your best bet. Only accessible rooms have grab bars for handicap access. No age restriction for check-in.

💡 Insider Tip: The first shuttle at 5:58 AM is ideal for early appointments—grab a schedule at check-in to plan your returns.
Why We Love It: Walkable location plus a reliable shuttle for the Mayo Clinic complex.

Choose this if: You want the flexibility of walking or shuttling to the clinic without parking costs.

âś“ Live rate check across booking sitesâś“ No signup needed

Check Tonight’s Price for SpringHill Suites Rochester Mayo Clinic Area / Saint Marys →

20. Hampton Inn & Suites Rochester-North

At a Glance

  • Type: Hotel
  • Area: 59th Street NW, about 6 miles from Mayo Clinic 📍 View on map
  • Rating: 8.6/10 – Excellent (150+ reviews)
  • Top Score: Cleanliness 9.2
  • Check-in: From 3:00 PM to 11:00 PM
  • Check-out: Until 11:00 AM
  • Standout: Best breakfast on the list & free shuttle Monday-Friday

Guest Scores

  • Cleanliness9.2
  • Location8.9
  • Comfort9.1
  • Staff9.0
  • Value8.5
  • Facilities8.8

The Vibe

An “Excellent” rated 3-star near Mayo Clinic Rochester MN with a cleanliness score of 9.2 and comfort at 9.1. Staff scores 9.0, and guests consistently call the breakfast “the best found in a hotel.” The free shuttle runs Monday-Friday from 6 AM to 9 PM on the half-hour by request. The indoor swimming pool and free on-site parking add serious value.

What You Actually Get

All studio suites are 40% larger than standard rooms and include a full-size sofa sleeper—great if you’re traveling with a companion. Free Wi-Fi (7.5) is adequate, and the “good breakfast” rating undersells it; guests rave about the variety of options and all-day coffee availability. The free shuttle covers Mayo Clinic and requires a request—call the front desk when you’re ready for pickup. Pets are not allowed. Mayo Clinic discounts are available when booking directly with the hotel or through the Hilton website. Groups booking more than 9 rooms face different policies. Check-in by 11 PM—late arrivals should call ahead.

💡 Insider Tip: The all-day coffee and tea bar is a lifesaver—grab a cup before the shuttle or after returning from appointments.
Why We Love It: The best breakfast spread in Rochester with a shuttle that runs until 9 PM.

Choose this if: You want the best included breakfast and don’t mind a short drive for superior room space.

âś“ Live rate check across booking sitesâś“ No signup needed

Check Tonight’s Price for Hampton Inn & Suites Rochester-North →

Final Verdict: Our Top 3 Picks

🏆 Best Overall

#18 Home2 Suites by Hilton Rochester Mayo Clinic Area

Highest overall rating (9.3), spotless 9.5 cleanliness, full kitchen suite, and a reliable weekday shuttle—this is the complete package for clinic travelers.

Check Tonight’s Price for Home2 Suites by Hilton Rochester Mayo Clinic Area →

đź’° Best Value

#8 Quality Inn & Suites Mayo Clinic Area

Value score of 8.9 is the highest on the list—spacious recliner rooms, 9.0 location, and free breakfast at a budget-friendly price.

Check Tonight’s Price for Quality Inn & Suites Mayo Clinic Area →

đźš¶ Best Walk Access

#16 Kahler Grand Hotel

A 4-minute walk to Plummer Building with Wi-Fi scoring 9.5—historic character meets unbeatable proximity for appointment-focused stays.

Check Tonight’s Price for Kahler Grand Hotel →

How We Ranked These Rochester Hotels

We evaluated 20 properties near Mayo Clinic Rochester MN against 7,400+ verified guest reviews to find the best balance of proximity, cleanliness, and value. Each hotel had to score 7.0+ overall and maintain 10+ reviews to be considered.

  • Guest score thresholds: Only properties with 7.0+ overall and 10+ verified reviews
  • Score breakdown analysis: Prioritized cleanliness, location, and value—the categories that drive repeat bookings for medical travelers
  • Amenity verification: Cross-referenced advertised shuttle services and breakfast quality against guest review patterns
  • Proximity signals: Measured walking distance and shuttle schedules to Mayo Clinic’s main buildings and St. Mary’s campus

Frequently Asked Questions

Which hotels near Mayo Clinic Rochester MN offer free shuttle service?

At least 12 properties on this list provide complimentary shuttle service to Mayo Clinic. The widest window belongs to Centerstone Plaza Hotel (5:30 AM–10 PM, seven days a week). Microtel Inn & Suites starts at 6:05 AM, and Home2 Suites runs from 5:15 AM to 6:15 PM on weekdays. Most shuttles require a schedule pickup at check-in—some need same-day requests. Always confirm operating hours and weekend availability when booking.

What’s the closest hotel walking distance to Mayo Clinic?

The Kahler Grand Hotel is the closest at a 4-minute walk from Plummer Building (9.1 location score). The Hilton Garden Inn Rochester Downtown connects via skywalk—you can walk to the clinic without stepping outside. EVEN Hotel Rochester is a 13-minute walk, and SpringHill Suites Saint Marys is a 14-minute walk. For those who prefer not to drive or shuttle, these are your best options.

Do these hotels offer discounts for Mayo Clinic patients?

Yes—several properties offer Mayo Clinic patient discounts, but they’re often only available when booking directly with the hotel. Med City Inn, Centerstone Plaza, Best Western Rochester, EVEN Hotel, Hyatt House, Kahler Grand, and Hampton Inn North all confirmed patient rates in guest Q&As. The Hyatt House offers 15% off. Always call the property directly to inquire about patient pricing—online rates from third-party sites rarely include these discounts.

Which hotels near Mayo Clinic are pet-friendly?

Eight properties on this list allow pets. La Quinta South has the cheapest pet fee at $20 per stay (caps at $40 for longer stays). Comfort Inn & Suites Rochester South charges a $25 one-time fee. Spark by Hilton charges $15 per pet per night. AmericInn charges $50 per stay. EVEN Hotel, Centerstone Plaza, Best Western, and Home2 Suites all allow pets with charges. Always confirm the fee structure and pet-friendly room availability when booking.

What’s the best time to visit Rochester, Minnesota for a Mayo Clinic appointment?

Spring (May–June) and fall (September–October) offer the mildest weather for walking to the clinic. Winter (November–March) brings snow and cold—the Hilton Garden Inn’s skywalk connection becomes invaluable. Summer (July–August) is warm but humid. For hotel pricing, weekdays tend to be more expensive due to appointment demand. If your schedule allows, Sunday arrivals and Thursday departures sometimes capture lower rates. Book at least 2-3 weeks out for the best availability near the clinic.

How do I get from Rochester International Airport (RST) to my hotel near Mayo Clinic?

Several hotels offer free airport shuttles—Comfort Inn & Suites Rochester South and Holiday Inn Express Rochester South both include complimentary RST transfers. For properties without airport shuttles, rideshare services (Uber/Lyft) cost roughly $10-20 to downtown hotels. Taxis are available at the airport terminal. If you’re renting a car, note that many hotels near Mayo Clinic offer free parking—Med City Inn, Microtel Inn, and Super 8 all include complimentary on-site parking.